Since 1980, Dr. Jerilynn C. Prior and colleagues have been studying women’s menstrual cycles and ovulation. A focus has been on longitudinal observational studies analyzing within-woman changes in response to, for example, exercise training or chemotherapy for breast cancer. Documented changes occur within the menstrual cycle and ovulation, in physical and emotional experiences and in bone mineral density and bone metabolism. Another primary focus for research is using randomized controlled trials to assess the effects of progesterone therapy on metabolism, endothelial function, hot flushes/night sweats, experiences and bone changes.
The Centre for Menstrual Cycle and Ovulation Research philosophy is that each participant becomes part of the research team, is provided her own and preliminary results and provides feedback on the project. Dr. Prior personally undergoes all research interventions before they are approved as part of any research.
The Centre for Menstrual Cycle Research and Ovulation undertakes projects supported by pharmaceutical companies only if the research is designed, conducted and analyzed by CeMCOR scientists. It will also not accept support unless whatever results are discovered can be submitted for publication.
The research focus for CeMCOR is broadening to include the epidemiology of women’s reproduction. Data from the Canadian Multicentre Osteoporosis Study relating to women’s reproduction will be examined using both the baseline and 5-yr databases. For background to this analysis, Drs. Jerilynn C. Prior and Siri Forsmo are completing an exhaustive review of women’s reproductive epidemiology.
CeMCOR previously used measured endpoints like bone change in studies of menstrual cycles and ovulation. CeMCOR is now focusing more closely on changes in women’s experiences collected using self-report instruments. The Menstrual Cycle Diary® database includes cycles collected over one year by more than 60 ovulatory women and by about 30 women with hypothalamic suppression of menstrual cycles or ovulation.
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