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Resources

The Centre for Menstrual Cycle and Ovulation Research has developed a number of tools and resources that healthcare workers may find helpful.

Progesterone Therapy for Symptomatic Perimenopause

Perimenopause, although characterized as a time of dropping estradiol involves chaotic estrogen levels that average >20% higher and intermittently are extremely high and ovulatory disturbances with decreasing progesterone levels. Perimenopause begins and is most symptomatic when cycles remain regular. Perimenopause is highly symptomatic for more than 20% of women--symptoms typically included heavy menstrual flow, night sweats, infertility, breast tenderness and sleep disturbances. Progesterone, because it normally counterbalances estradiol's actions, is effective treatment for heavy flow, probably night sweats, infertility and breast tenderness and definitely decreased anxiety and improves sleep.

Type: 
Articles
Life Phase: 
Perimenopause

Daily Menopause Diary

This diary is for women who have gone at least 12 months without a menstrual period
You will need the free Adobe Acrobat Reader in order to read and print them. If you don't already have this program, you can download it for free

Type: 
Diary
Life Phase: 
Menopause

WHI, Five Years Later–WHY no Change

The Women’s Health Initiative (WHI) Estrogen plus Progestin (E plus P) trial was prematurely stopped because it caused harm (1). Until the Estrogen in women with hysterectomy arm (E only) of the WHI was also halted prematurely in 2004 (2), progestin was blamed for the lack of heart disease prevention. But now, five years later, doctors and media are still discussing Hormone Replacement Therapy (HRT) and menopause as estrogen deficiency. The fundamental question is: Given these huge, great science WHI studies showing harm is caused by HRT, why has medicine not changed?

Type: 
Articles
Life Phase: 
Perimenopause, Menopause

Estrogen Deficiency: The Wrong Idea About Menopause

The largest and best-controlled trial testing whether hormone “replacement” therapy prevented heart disease was stopped three years early in July 2002. The Women’s Heath Initiative (WHI) study included over 16,600 healthy menopausal women without symptoms. These women were randomized to daily conjugated equine estrogen (Premarin, 0.625 mg) plus medroxyprogesterone (Provera, 2.5 mg) or an identical placebo. Hormone therapy increased breast cancer significantly (by 26% over placebo) and caused higher rates of heart attacks (29%), strokes (41%) and blood clots (211%). These risks outweighed this therapy’s significant benefits in preventing osteoporotic fractures of the hip (decreased by 34%) and colon cancer (decreased by 36%).
Since July 2002,hundreds of talk shows and editorials across North America have discussed these results. Many doctors and medical groups have offered criticisms. However, no one has yet identified what I believe is most important.

Type: 
Articles
Life Phase: 
Menopause

Pages

Estrogen’s Storm Season: Stories of Perimenopause

Estrogen's Storm Season

by Dr. Jerilynn C Prior

New second edition available

Estrogen’s Storm Season is now available in BOTH print and eBook (Mobi and ePUB) versions!

All royalties support CeMCOR research.

It is full of lively, realistic stories with which women can relate and evidence-based, empowering perimenopause information. It was a finalist in 2006 for the Independent Publisher Book Award in Health.

Purchase your ebook copy via our Amazon Kindle or
Google Play storefronts!

Paperback copies (with updated insert) still available here.

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Get Involved

Volunteer research participants are the heart of all CeMCOR research. Participants are invited to provide feedback on study processes, to learn their own results and at the end of a study, be the first to hear what the whole study found. Please become a CeMCOR research participant—you can contribute to improving the scientific information available for daughters, friends and the wider world of women.